Useful Genetics Part 1

Rosemary Redfield, The University of British Columbia

This college-level course gives students a thorough understanding of gene function, and enables them to apply this understanding to real-world issues, both personal and societal. This is Part 1 of a two-part course; Part 2 focuses on the study of of how genes and traits are inherited.


Image source: XKCD

Course philosophy

This short article describes the ideas behind Useful Genetics: Why do we have to learn this stuff? A new genetics for 21st century students

Who might want to take this course?

  • People affected by or concerned about a genetic disease (either directly or in a family member)
  • People interested in the genetic diversity of humans or other species
  • People who have had (or are considering having) their genes or genomes analyzed by companies such as 23andMe
  • People concerned about the public use of personal genetic information
  • People interested in breeding animals or plants, or in in conservation of endangered species
  • People interested in genealogy and ancestry analysis
  • Health care professionals
  • Science teachers
  • Anyone interested in genetics but unable to enroll in university at this time

Syllabus

Useful Genetics is taught in two parts.  Students in Part 1 may want to also sign up for the separate course Useful Genetics Part 2.

Part 1.  Genes and their effects (6 weekly modules plus a final exam week)

Module 1. How different are we?  Introduction to DNA, genes and chromosomes and the relationships between human populations.  Ancestral interbreeding with Neanderthals.

Module 2. How DNA molecules change.  The causes and immediate consequences of mutations.

Module 3. DNA differences and gene functions.  How mutations that change gene activity or function affect the properties of organisms.  

Module 4. Mutations in regulatory genes. How mutations cause cancer. Sex determination and genes on sex chromosomes. 

Module 5.  Natural genetic variation. How natural genetic variation is studied, and how it differs from classical alleles. Heritability and genome-wide association studies.  Genetic variation for cancer risks.

Module 6.  Personal genomics.  Kinds of DNA typing and genome analysis, and what can be learned from them about health risks, personal attributes and ancestry.

Part 2.  Inheritance (taught as the separate course Useful Genetics Part 2)  (5 weekly modules plus a final exam week)

Module 7.  The mechanics of inheritance.  How genes and chromosomes are transmitted through the generations (including the molecular mechanisms of mitosis and meiosis).

Module 8.  Genetic analysis.  Using genetic crosses as a research tool to investigate how genes work and what they do.  Sex-linkage, pedigree analysis, and hypothesis testing.

Module 9. All about breeding and inbreeding.  More about heritability and association studies. Inbreeding in humans, crops and livestock, and evolution. Hybrids and genetically modified organisms.

Module 10.  Chromosomal changes.  Changes in the number of chromosomes and in how genes are arranged on them.  Genome evolution.

Module 11.  Selected advanced topics.  The origin of life, mitochondrial genes and mutations, genetic mosaicism, fetal DNA in mothers, epigenetic inheritance, and other topics students may suggest.

Recommended Background

You will need some prior knowledge of basic biology (first-year college or a recent good high-school course).  A self-assessment pre-test will be provided to students who enroll in the course, and additional activities and readings will be made available for students who want to improve their preparation.

Suggested Readings

The course will use free online textbooks as its primary reading resource.  Links to these and to preparatory readings for students with little biology background will be provided before the course starts.

Course Format

The two parts of Useful Genetics consist of six (Part 1) and five (Part 2) weekly modules, each comprising about 15 explanatory videos (5-15 minutes in length) and two challenging quizzes (self-test problems and graded homework problems).  Each part's modules are accompanied by two peer-assessed explanation assignments and followed by a final exam.

FAQ

Statements of Accomplishment: Students who earn 50% or better will receive a Statement of Accomplishment; those earning 80% or better will receive a Statement of Accomplishment with Distinction.

Verified Certificates: Students may choose to enroll in the optional Signature Track, which provides an identity-verified Certificate.
会期:
  • 2014年9月05日, 6 星期
  • 2013年11月01日, 6 星期
  • 2013年5月01日, 12 星期
  • 日期还没有被通知, 6 星期
介绍:
  • 免费:
  • 收费:
  • 证书:
  • MOOC:
  • 视频讲座:
  • 音频讲座:
  • Email-课程:
  • 语言: 英语 Gb

反馈

目前这个课程还没有反馈。您想要留第一个反馈吗?

请注册, 为了写反馈

Show?id=n3eliycplgk&bids=695438
已经在列表:
700-helix-verified-262x136 Introduction to Biology
Introductory courses into biochemistry, molecular biology, genetics and evolution...
NVIDIA
还有这个题目的:
9-19js01 Cognitive & Behavioral Genetics
How genetics can add to our understanding of cognition, language, emotion, personality...
Icon2culture Useful Genetics Part 2
This college-level course gives students a thorough understanding of genetic...
Regular_1773392a-c546-49f6-b52a-bee15ce2a57a Inside Cancer: How Genes Influence Cancer Development
Understand how genetics influence the development and spread of cancer, with...
Genes Genes and the Human Condition (From Behavior to Biotechnology)
To acquire an understanding of the fundamental concepts of genomics and biotechnology...
Hst-161f07 Molecular Biology and Genetics in Modern Medicine
This course provides a foundation for understanding the relationship between...
还有标题«医学与健康»:
989da941-badf-4b02-acf5-198c22a2370e-baad411d7ffc.small Digital Biomaterials
Learn and discover the special, exciting and new materials and technologies...
Regular_a45e1791-4619-4c75-a5eb-98ee33da42b1 Logical and Critical Thinking
Improve your logical and critical thinking skills in this free online course...
Regular_5776e8c0-c46f-4a65-869b-24d8491fc59d Health Technology Assessment: Choosing Which Treatments Get Funded
Before new drugs or treatments are adopted, their effectiveness and cost must...
Regular_369d2629-041c-41e9-a012-e39f9573ecb7 The Many Faces of Dementia
Gain a unique insight into dementia through the stories, symptoms and science...
Regular_62c442cf-a19c-42d5-a643-039146709a1d Talking About Cancer: Reducing Risk, Early Detection and Mythbusting
1 in 2 people will develop cancer in their lifetime. At Cancer Research UK we...
还有Coursera:
Success-from-the-start-2 First Year Teaching (Secondary Grades) - Success from the Start
Success with your students starts on Day 1. Learn from NTC's 25 years developing...
New-york-city-78181 Understanding 9/11: Why Did al Qai’da Attack America?
This course will explore the forces that led to the 9/11 attacks and the policies...
Small-icon.hover Aboriginal Worldviews and Education
This course will explore indigenous ways of knowing and how this knowledge can...
Ac-logo Analytic Combinatorics
Analytic Combinatorics teaches a calculus that enables precise quantitative...
Talk_bubble_fin2 Accountable Talk®: Conversation that Works
Designed for teachers and learners in every setting - in school and out, in...

© 2013-2019